
Four mature women live together in Miami and experience the joys and angst of their golden years; strong-willed Dorothy, spacey Rose, lusty Southern belle Blanche and matriarch Sophia, Dorothy's mom, occasionally clash but are there for one another in the end; after all, when the show's theme song is titled "Thank You for Being a Friend," the ladies have to remain friendly with one another.
Blanche and Rose despise one of Dorothy's friends, the novelist Barbara Thorndyke.
Blanche, Dorothy and Sophia cheer up a hospitalized Rose after she becomes ill at a crashed class reunion.
Before waking from surgery, Rose dreams that she, Blanche and Dorothy are 100 years in the future.
Blanche pairs Dorothy with her visiting uncle (Leslie Nielsen), but later regrets her matchmaking.