A women's health clinic in Philadelphia is the setting for this drama. While dealing with a number of medical issues, the show often revolves around the conflict between the clinic's directors: one a passionate advocate for patients and the other a more discipline-oriented doctor.
Dana's ex-fiance comes to her when he finds a lump in his breast; a diabetic is mistaken to be a drunk driver.
Dana treats a figure skater with Olympic dreams for osteoporosis; a pregnant patient who is being sued by her ex-boyfriend seeks treatment.
An Amish woman showing symptoms of mad cow disease enters the clinic; Lu finds out that Lana is suffering from sexual dysfunction.
Dana treats a pregnant politician with severe eclampsia; Lu diagnoses a patient, who has been lying about her age, with menopause.